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Knit directory: madi-biostat-project3-SDY8003-Thailand/

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html 19a62eb f006zvn1 2024-10-16 fixed categorical labels
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html 3a356e9 f006zvn1 2024-10-16 JIVE updated with covariates
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Dataset

Unstandardized

Joint and Individual Variance Explained (JIVE):

Analytes were categorized into IgG, Fc Receptors, and Effector Functions, with data from each category analyzed using the JIVE algorithm to decompose shared (joint) and unique (individual) variation components.

Matrix Rank (number of pricincipal components selected) was determined by significance testing as part of the JIVE algorithm. Principal components that explained a statistically significant amount of variance at α = 0.05 were retained, while all others were excluded.

Vaccinated

Joint Matrix Rank: 2

Individual Matrices Rank:

  • IgG: 5

  • FcR: 4

  • Effector Functions: 2

Original Matrices Rank:

  • IgG: 33

  • FcR: 12

  • Effector Functions: 16

Variation Explained

Version Author Date
d6f0da4 f006zvn1 2024-10-29
Joint PCA

Version Author Date
d6f0da4 f006zvn1 2024-10-29
Joint + Individual PCA

Version Author Date
d6f0da4 f006zvn1 2024-10-29
PC Loadings
Joint

Version Author Date
9f50e73 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19

Version Author Date
9f50e73 alecbuetow 2024-11-20
0cc81b6 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19
IgG

Version Author Date
9f50e73 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19

Version Author Date
9f50e73 alecbuetow 2024-11-20
0cc81b6 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19
FcR

Version Author Date
9f50e73 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19

Version Author Date
9f50e73 alecbuetow 2024-11-20
0cc81b6 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19
Effector

Version Author Date
9f50e73 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19

Version Author Date
9f50e73 alecbuetow 2024-11-20
0cc81b6 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19
Classification

Version Author Date
d6f0da4 f006zvn1 2024-10-29

Subjects above the line are classified into one group (‘Above at Vaccinated Visit’) as are subjects below the line (‘Below at Vaccinated Visit’)

Boosted

Joint Matrix Rank: 1

Individual Matrices Rank:

  • IgG: 3

  • FcR: 2

  • Effector Functions: 1

Original Matrices Rank:

  • IgG: 33

  • FcR: 12

  • Effector Functions: 16

Variation Explained

Version Author Date
d6f0da4 f006zvn1 2024-10-29
Joint PCA

Version Author Date
d6f0da4 f006zvn1 2024-10-29
Joint + Individual PCA

Version Author Date
d6f0da4 f006zvn1 2024-10-29
PC Loadings
Joint

Version Author Date
9f50e73 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19

Version Author Date
366e256 alecbuetow 2024-11-19
IgG

Version Author Date
9f50e73 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19

Version Author Date
9f50e73 alecbuetow 2024-11-20
0cc81b6 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19
FcR

Version Author Date
366e256 alecbuetow 2024-11-19

Version Author Date
9f50e73 alecbuetow 2024-11-20
0cc81b6 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19
Effector

Version Author Date
9f50e73 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19

Version Author Date
366e256 alecbuetow 2024-11-19
Classification

Version Author Date
d6f0da4 f006zvn1 2024-10-29

Subjects above the line are classified into one group (‘Above at Boosted Visit’) as are subjects below the line (‘Below at Boosted Visit’)

Classification Analysis:

Subject classifications were derived from clusters appearing in the JIVE plots above. If no latent clusters were evident, then subject classifications are unavailable.

Vaccinated vs Boosted Classification
Below Above
Below 31 11
Above 0 40
Correlation = 0.761

Vaccinated

Classification by Arm
Arm Classification Number of Subjects
maternal Tdap - infant wp Below 19
maternal Tdap - infant wp Above 22
maternal Tdap - infant wp NA 1
No maternal vaccination - infant wp Below 25
No maternal vaccination - infant wp Above 22
No maternal vaccination - infant wp NA 3

Subjects who are missing all data within any given domain (IgG, FcR, or Effector) cannot be classified and are marked as NA.

Birth Weight

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

CMV Seropositivity
Classification by CMV Seropositivity
Below Above
No 30 0
Yes 11 40
Unknown 3 4
P-Value = 4.16e-13

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Infant Sex
Classification by Infant Sex
Below Above
Male 23 25
Female 21 19
P-Value = 0.831

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Delivery Mode
Classification by Delivery Mode
Below Above
Vaginal 18 20
Caesarian 26 24
P-Value = 0.83

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Parity
Classification by Parity
Below Above
0 19 23
1 20 14
2 4 6
3 1 1
P-Value = 0.655

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Gravidity
Classification by Gravidity
Below Above
1 16 21
2 20 15
3 7 5
4 1 2
5 0 1
P-Value = 0.576

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Gestational Age at Vaccine

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Infant Interval Between Vaccination and Delivery Days

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Gestational Age at Delivery

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Maternal Age at Delivery

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

IgG
DT_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

ELISA_FHA_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

ELISA_PRN_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

ELISA_PT_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FcR
DT_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Effector
DT_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Boosted

Classification by Arm
Arm Classification Number of Subjects
maternal Tdap - infant wp Below 13
maternal Tdap - infant wp Above 25
maternal Tdap - infant wp NA 2
No maternal vaccination - infant wp Below 20
No maternal vaccination - infant wp Above 28
No maternal vaccination - infant wp NA 0

Subjects who are missing all data within any given domain (IgG, FcR, or Effector) cannot be classified and are marked as NA.

Birth Weight

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

CMV Seropositivity
Classification by CMV Seropositivity
Below Above
No 31 1
Yes 1 52
Unknown 1 0
P-Value = 2.68e-21

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Infant Sex
Classification by Infant Sex
Below Above
Male 17 32
Female 16 21
P-Value = 0.503

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Delivery Mode
Classification by Delivery Mode
Below Above
Vaginal 16 20
Caesarian 17 33
P-Value = 0.373

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Parity
Classification by Parity
Below Above
0 12 28
1 16 18
2 4 6
3 1 1
P-Value = 0.441

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Gravidity
Classification by Gravidity
Below Above
1 10 24
2 15 19
3 6 7
4 2 2
5 0 1
P-Value = 0.595

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Gestational Age at Vaccine

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Infant Interval Between Vaccination and Delivery Days

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Gestational Age at Delivery

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Maternal Age at Delivery

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

IgG
DT_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

ELISA_FHA_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

ELISA_PRN_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

ELISA_PT_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FcR
DT_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Effector
DT_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Citations:

Michael J. O’Connell, Eric F. Lock, R.JIVE for exploration of multi-source molecular data, Bioinformatics, Volume 32, Issue 18, September 2016, Pages 2877–2879, https://doi.org/10.1093/bioinformatics/btw324

Eric F. Lock, Katherine A. Hoadley, J. S. Marron, Andrew B. Nobel, “Joint and individual variation explained (JIVE) for integrated analysis of multiple data types,” The Annals of Applied Statistics, Ann. Appl. Stat. 7(1), 523-542, (March 2013), https://doi.org/10.1214/12-AOAS597

Standardized by Total IgG

Joint and Individual Variance Explained (JIVE):

Analytes were categorized into IgG, Fc Receptors, and Effector Functions, with data from each category analyzed using the JIVE algorithm to decompose shared (joint) and unique (individual) variation components.

Matrix Rank (number of pricincipal components selected) was determined by significance testing as part of the JIVE algorithm. Principal components that explained a statistically significant amount of variance at α = 0.05 were retained, while all others were excluded.

Vaccinated

Joint Matrix Rank: 1

Individual Matrices Rank:

  • IgG: 2

  • FcR: 2

  • Effector Functions: 1

Original Matrices Rank:

  • IgG: 33

  • FcR: 12

  • Effector Functions: 16

Variation Explained

Version Author Date
bde08e9 alecbuetow 2024-11-04
d6f0da4 f006zvn1 2024-10-29
Joint PCA

Version Author Date
d6f0da4 f006zvn1 2024-10-29
Joint + Individual PCA

Version Author Date
bde08e9 alecbuetow 2024-11-04
d6f0da4 f006zvn1 2024-10-29
PC Loadings
Joint

Version Author Date
366e256 alecbuetow 2024-11-19

Version Author Date
366e256 alecbuetow 2024-11-19
IgG

Version Author Date
366e256 alecbuetow 2024-11-19

Version Author Date
9f50e73 alecbuetow 2024-11-20
0cc81b6 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19
FcR

Version Author Date
366e256 alecbuetow 2024-11-19

Version Author Date
9f50e73 alecbuetow 2024-11-20
0cc81b6 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19
Effector

Version Author Date
9f50e73 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19

Version Author Date
366e256 alecbuetow 2024-11-19
Classification

Version Author Date
d6f0da4 f006zvn1 2024-10-29

Boosted

Joint Matrix Rank: 2

Individual Matrices Rank:

  • IgG: 1

  • FcR: 1

  • Effector Functions: 2

Original Matrices Rank:

  • IgG: 33

  • FcR: 12

  • Effector Functions: 16

Variation Explained

Version Author Date
bde08e9 alecbuetow 2024-11-04
d6f0da4 f006zvn1 2024-10-29
Joint PCA

Version Author Date
bde08e9 alecbuetow 2024-11-04
d6f0da4 f006zvn1 2024-10-29
Joint + Individual PCA

Version Author Date
bde08e9 alecbuetow 2024-11-04
d6f0da4 f006zvn1 2024-10-29
PC Loadings
Joint

Version Author Date
9f50e73 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19

Version Author Date
9f50e73 alecbuetow 2024-11-20
0cc81b6 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19
IgG

Version Author Date
9f50e73 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19

Version Author Date
366e256 alecbuetow 2024-11-19
FcR

Version Author Date
366e256 alecbuetow 2024-11-19

Version Author Date
366e256 alecbuetow 2024-11-19
Effector

Version Author Date
9f50e73 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19

Version Author Date
9f50e73 alecbuetow 2024-11-20
0cc81b6 alecbuetow 2024-11-20
366e256 alecbuetow 2024-11-19
Classification

Version Author Date
d6f0da4 f006zvn1 2024-10-29

Classification Analysis:

Subject classifications were derived from clusters appearing in the JIVE plots above. If no latent clusters were evident, then subject classifications are unavailable.

Vaccinated vs Boosted Classification
Below Above
Below 0 0
Above 0 0
Correlation = NA

Vaccinated

Version Author Date
d6f0da4 f006zvn1 2024-10-29

Subjects who are missing all data within any given domain (IgG, FcR, or Effector) cannot be classified and are marked as NA.

Birth Weight

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

CMV Seropositivity
Classification by CMV Seropositivity
Below Above
No 0 0
Yes 0 0
Unknown 0 0
P-Value = NA

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Infant Sex
Classification by Infant Sex
Below Above
Male 0 0
Female 0 0
P-Value = NA

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Delivery Mode
Classification by Delivery Mode
Below Above
Vaginal 0 0
Caesarian 0 0
P-Value = NA

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Parity
Classification by Parity
Below Above
0 0 0
1 0 0
2 0 0
3 0 0
P-Value = NA

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Gravidity
Classification by Gravidity
Below Above
1 0 0
2 0 0
3 0 0
4 0 0
5 0 0
P-Value = NA

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Gestational Age at Vaccine

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Infant Interval Between Vaccination and Delivery Days

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Gestational Age at Delivery

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Maternal Age at Delivery

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

IgG
DT_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

ELISA_FHA_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

ELISA_PRN_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

ELISA_PT_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FcR
DT_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Effector
DT_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Boosted

Version Author Date
d6f0da4 f006zvn1 2024-10-29

Subjects who are missing all data within any given domain (IgG, FcR, or Effector) cannot be classified and are marked as NA.

Birth Weight

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

CMV Seropositivity
Classification by CMV Seropositivity
Below Above
No 0 0
Yes 0 0
Unknown 0 0
P-Value = NA

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Infant Sex
Classification by Infant Sex
Below Above
Male 0 0
Female 0 0
P-Value = NA

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Delivery Mode
Classification by Delivery Mode
Below Above
Vaginal 0 0
Caesarian 0 0
P-Value = NA

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Parity
Classification by Parity
Below Above
0 0 0
1 0 0
2 0 0
3 0 0
P-Value = NA

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Gravidity
Classification by Gravidity
Below Above
1 0 0
2 0 0
3 0 0
4 0 0
5 0 0
P-Value = NA

P-Values are calculated from Fisher’s Exact Test with no FDR correction.

Gestational Age at Vaccine

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Infant Interval Between Vaccination and Delivery Days

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Gestational Age at Delivery

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Maternal Age at Delivery

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

IgG
DT_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG1

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG2

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG3

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG4

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

ELISA_FHA_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

ELISA_PRN_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

ELISA_PT_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_IgG

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FcR
DT_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_FcgR2a

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_FcgR3b

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Effector
DT_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

DT_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

FHA_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

gB_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PRN_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

PT_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_ADCD

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_ADCP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

TT_ADNP

Version Author Date
d6f0da4 f006zvn1 2024-10-29

P-Values are calculated from a two tailed T-Test with no FDR correction.

Citations:

Michael J. O’Connell, Eric F. Lock, R.JIVE for exploration of multi-source molecular data, Bioinformatics, Volume 32, Issue 18, September 2016, Pages 2877–2879, https://doi.org/10.1093/bioinformatics/btw324

Eric F. Lock, Katherine A. Hoadley, J. S. Marron, Andrew B. Nobel, “Joint and individual variation explained (JIVE) for integrated analysis of multiple data types,” The Annals of Applied Statistics, Ann. Appl. Stat. 7(1), 523-542, (March 2013), https://doi.org/10.1214/12-AOAS597


sessionInfo()
R version 4.4.2 (2024-10-31)
Platform: aarch64-apple-darwin20
Running under: macOS Sequoia 15.1.1

Matrix products: default
BLAS:   /Library/Frameworks/R.framework/Versions/4.4-arm64/Resources/lib/libRblas.0.dylib 
LAPACK: /Library/Frameworks/R.framework/Versions/4.4-arm64/Resources/lib/libRlapack.dylib;  LAPACK version 3.12.0

locale:
[1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8

time zone: America/New_York
tzcode source: internal

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
 [1] broom_1.0.7        e1071_1.7-16       glue_1.8.0         RPostgres_1.4.7   
 [5] DT_0.33            data.table_1.16.2  DBI_1.2.3          RColorBrewer_1.1-3
 [9] ggforce_0.4.2      ggpubr_0.6.0       gt_0.11.1          knitr_1.48.1      
[13] here_1.0.1         magrittr_2.0.3     r.jive_2.4         lubridate_1.9.3   
[17] forcats_1.0.0      stringr_1.5.1      dplyr_1.1.4        purrr_1.0.2       
[21] readr_2.1.5        tidyr_1.3.1        tibble_3.2.1       ggplot2_3.5.1     
[25] tidyverse_2.0.0   

loaded via a namespace (and not attached):
 [1] tidyselect_1.2.1   farver_2.1.2       blob_1.2.4         bitops_1.0-9      
 [5] fastmap_1.2.0      tweenr_2.0.3       promises_1.3.0     digest_0.6.37     
 [9] timechange_0.3.0   lifecycle_1.0.4    compiler_4.4.2     rlang_1.1.4       
[13] sass_0.4.9         tools_4.4.2        utf8_1.2.4         yaml_2.3.10       
[17] ggsignif_0.6.4     labeling_0.4.3     htmlwidgets_1.6.4  bit_4.5.0         
[21] plyr_1.8.9         xml2_1.3.6         abind_1.4-8        KernSmooth_2.23-24
[25] workflowr_1.7.1    withr_3.0.1        grid_4.4.2         polyclip_1.10-7   
[29] fansi_1.0.6        git2r_0.33.0       caTools_1.18.3     colorspace_2.1-1  
[33] scales_1.3.0       gtools_3.9.5       MASS_7.3-61        cli_3.6.3         
[37] crayon_1.5.3       rmarkdown_2.28     generics_0.1.3     rstudioapi_0.16.0 
[41] reshape2_1.4.4     tzdb_0.4.0         commonmark_1.9.2   proxy_0.4-27      
[45] cachem_1.1.0       vctrs_0.6.5        jsonlite_1.8.9     carData_3.0-5     
[49] car_3.1-3          hms_1.1.3          bit64_4.5.2        rstatix_0.7.2     
[53] Formula_1.2-5      jquerylib_0.1.4    stringi_1.8.4      gtable_0.3.5      
[57] later_1.3.2        munsell_0.5.1      pillar_1.9.0       htmltools_0.5.8.1 
[61] gplots_3.2.0       R6_2.5.1           rprojroot_2.0.4    evaluate_1.0.1    
[65] markdown_1.13      highr_0.11         backports_1.5.0    httpuv_1.6.15     
[69] bslib_0.8.0        class_7.3-22       Rcpp_1.0.13        whisker_0.4.1     
[73] xfun_0.48          fs_1.6.4           pkgconfig_2.0.3