guides:ppintro
Differences
This shows you the differences between two versions of the page.
| Next revision | Previous revision Next revision Both sides next revision | ||
|
guides:ppintro [2013/06/01 22:06] mvdm created |
guides:ppintro [2013/06/01 22:19] mvdm |
||
|---|---|---|---|
| Line 1: | Line 1: | ||
| The basic phase precession phenomenon is apparent when you look at the timing of place cell spikes relative to the hippocampal theta rhythm: | The basic phase precession phenomenon is apparent when you look at the timing of place cell spikes relative to the hippocampal theta rhythm: | ||
| + | {{ :guides:sm_rwc_mvdm_fig1.png?600 |}} | ||
| + | (Figure from Malhotra et al. 2012) Each spike is assigned a color based on the /phase/ of the theta rhythm (a component of the LFP or "local field potential") at which it occurs. Note the smooth color change as the animal runs through the place field. | ||
| + | |||
| + | Thus, when looking at a typical place cell like the above, phase precession manifests as (1) a relationship between *location* on the maze and the theta phase of a place cell's spikes, as shown when plotting spikes "in space" and (2) a relationship between *time* and the theta phase of a place cell's spikes, as shown when plotting spikes "in time" aligned to the LFP. | ||
| + | |||
| + | When a rat runs through a place field, space and time will be correlated, so it is not a priori clear if either one is somehow "primary". There are numerous papers that explore this issue. | ||
| An important conceptual step is to extend this idea to what happens in a population of place cells which are all phase precessing: | An important conceptual step is to extend this idea to what happens in a population of place cells which are all phase precessing: | ||
guides/ppintro.txt ยท Last modified: 2018/07/07 10:19 (external edit)
Page Tools
Except where otherwise noted, content on this wiki is licensed under the following license: CC Attribution-Share Alike 4.0 International
